Reports

These publications are the output of RSPCA-led expert working groups comprising scientists from academia and industry, veterinarians, animal technologists and other relevant stakeholders. Some cover broad issues associated with avoiding or reducing ‘severe’ suffering such as refinement, welfare assessment and the implementation of humane endpoints, whilst others provide guidance relating to specific models and procedures that have the potential to cause ‘severe’ suffering.

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    Showing 18 of 18 results

    Refining bone marrow ablation and reconstitution in mice

    Author: Hawkins et al.

    Publish date:13 September 2024

    • Mortality
    • Welfare assessment
    • Humane endpoints
    • Refinement
    • Cumulative severity

    Refining rodent cancer models

    Author: I. De Vleeschauwer et al.

    Publish date:11 July 2024

    • Welfare assessment
    • Humane endpoints
    • Refinement

    Fish acute toxicity test

    Author: Ioanna Katsiadaki et al.

    Publish date:15 October 2021

    • Mortality
    • Humane endpoints
    • Refinement

    Vaccine studies using NHP

    Author: J. Prescott et al.

    Publish date:19 March 2021

    • Welfare assessment
    • Humane endpoints
    • Refinement
    • Severe procedures

    Spinal cord injury

    Author: Lilley et al.

    Publish date:3 March 2020

    • Welfare assessment
    • Humane endpoints
    • Refinement
    • Severe procedures

    Avoiding mortality

    Author: Hawkins et al.

    Publish date:9 January 2019

    • Mortality
    • Welfare assessment
    • Humane endpoints

    Ischaemic stroke

    Author: Percie du Sert et al.

    Publish date:11 August 2017

    • Welfare assessment
    • Refinement
    • Lifetime experiences

    Epilepsy and seizures

    Author: Lidster et al.

    Publish date:15 September 2016

    • Welfare assessment
    • Humane endpoints
    • Refinement

    Epilepsy

    Author: Modebadze et al.

    Publish date:24 February 2016

    • Welfare assessment
    • Humane endpoints
    • Refinement
    • Cumulative severity

    Rheumatoid arthritis

    Author: Hawkins et al.

    Publish date:22 June 2015

    • Welfare assessment
    • Humane endpoints
    • Refinement
    • Lifetime experiences

    Sepsis

    Author: Lilley et al.

    Publish date:12 September 2014

    • Welfare assessment
    • Humane endpoints
    • Refinement

    Neuropathic pain

    Author: Percie du Sert et al.

    Publish date:16 February 2014

    • Refinement
    • Lifetime experiences
    • Cumulative severity

    Vaccine potency test

    Author: FM. Hendriksen

    Publish date:9 January 2014

    • Welfare assessment
    • Refinement
    • Severe procedures

    Liver fibrosis model

    Author: M E. Probert et al.

    Publish date:28 August 2013

    • Welfare assessment
    • Refinement
    • Lifetime experiences

    Experimental autoimmune encephalomyelitis

    Author: Wolfensohn et al.

    Publish date:18 January 2013

    • Welfare assessment
    • Humane endpoints
    • Refinement

    Seizures, convulsions and epilepsy

    Author: Wolfensohn et al.

    Publish date:13 September 2012

    • Welfare assessment
    • Humane endpoints
    • Refinement
    • Lifetime experiences

    Cancer research

    Author: Workman et al.

    Publish date:25 September 2010

    • Welfare assessment
    • Humane endpoints
    • Refinement

    Cardiovascular research

    Author: Emerson

    Publish date:22 September 2010

    • Refinement
    • Lifetime experiences
    • Severe procedures