The RSPCA has held a series of events, bringing together hundreds of people from across the world, with the aim of sharing knowledge and new ideas, and promoting practical approaches to help avoid or reduce severe suffering in animals used in research and testing. Participants usually include representatives from government authorities involved in the regulation of animal research, National Committees on animal experiments, and local Animal Welfare Bodies at institutions, veterinarians, scientists, animal facility managers, animal technologists, 3Rs centres and individuals involved in delivering education and training related to laboratory animal science.

Upcoming events will appear on this page.

11th World Congress on Alternatives and Animal Use in the Life Sciences – online, 2021

We convened a ‘Focus on Severe Suffering’ session, where speakers covered topics including:

  • reducing suffering in animal models of neuropathic and inflammatory pain, sepsis and colitis
  • tailoring humane endpoints
  • avoiding mortality
Focus on fish – online, 2021

Topics covered in our ‘virtual’ conference on practical refinements for fish used in research and testing, included:

  • what is it like to be a zebrafish
  • attitudes towards fish welfare and the 3Rs
  • using analgesia in fishes
  • refining procedures
  • welfare assessment
  • humane endpoints
focus on fish
3rd international meeting – Athens, 2019

The programme was based on the ‘Avoiding mortality in animal research and testing’ report, covering three main areas:

  • reducing the numbers of animals ‘found dead’
  • reducing unpredicted mortality of animals being used in procedures
  • challenging perceived requirements for ‘death as an endpoint’ in studies and tests
Meeting summary and action points: Athens (PDF 316KB)
3rd International meeting, Athens 2019

FELASA Congress – Prague, 2019

We were delighted to accept an invitation from the organisers of this event (which attracted over 2,000 delegates from across the world) to run three scientific sessions, on:

  • Ending severe suffering – where are we now?
  • Welfare assessment – recognising severe suffering
  • Practical refinements of ‘severe’ suffering animal models and procedures
FELASA Congress - Prague, 2019
Challenging refinements – Stevenage, 2019

The focus for this meeting was strategies for refining models and procedures in which this can be challenging, such as humane endpoints in regulatory tests, and analgesia provision in pain models. The programme included case studies from industry and academia, highlighting how pain, suffering, distress or lasting harm has been successfully avoided or reduced in specific models or procedures such as:

  • neuropathic pain
  • collagen-induced arthritis
  • experimental diabetes
  • evident toxicity in regulatory tests
  • environmental toxicity testing in fish

Plus discussion on:
how local AWERBs can assist in developing strategies to apply refinement in ‘challenging’ models improving dissemination of information on refinement

challenging refinements

SGV annual meeting – Zurich, 2017

We were thrilled to accept the Swiss Laboratory Animal Science Association annual 3Rs award in recognition of our work towards ending severe suffering by implementing humane endpoints, and to give the keynote presentation at their annual conference.

SGV annual meeting - Zurich, 2017
2nd international meeting – Berlin, 2017

The programme included

  • a series of case studies in which severe suffering had been successfully reduced
  • study areas where challenges and obstacles to reducing or avoiding severe suffering still remain
  • prospective severity of procedures
  • the harm-benefit assessment
  • communicating with the public about ‘harms’, and ‘severe’ suffering
  • the role of Animal Welfare Bodies, National Committees and others in sharing good practice
Meeting summary and action points: Berlin (PDF 433KB)
Focus on fish
1st international meeting – Brussels, 2016

The programme included

  • ‘severe’ suffering within the EU
  • how pain, suffering and distress are currently identified and assessed in animals
  • recent progress in refining procedures and animal care across a range of ‘models’, tests, techniques and species
  • future opportunities for refinement
  • current potential scientific and other obstacles that will need to be overcome
Meeting summary and action points: Brussels (PDF 108KB)
1st International Meeting, Brussels, 2016


Avoiding and reducing severe suffering helps to fulfil legal requirements, reduce ethical concerns and improve scientific quality – this website will help you to achieve this.

Practical ways to reduce or avoid severe suffering include: